Povidone (PVP K Series) for Pharmaceutical Formulations

Yuking supplies Povidone, also known as Polyvinylpyrrolidone or PVP, in K15, K17, K25, K30 and K90 grades. This water-soluble polymer series is used in pharmaceutical formulations where controlled binding, film-forming, stabilization, solubilization support or viscosity adjustment is required.

Povidone is a white to milky-white powder with good solubility in water, methanol and ethanol. Its K value is closely related to molecular weight and solution viscosity, making grade selection an important part of formulation development.

CAS No.: 9003-39-8
Available Grades: PVP K15, PVP K17, PVP K25, PVP K30, PVP K90
Standard Packaging: 25 kg cardboard drum
Storage: Keep shaded, sealed and protected from moisture.

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Choose the Right PVP Grade for Your Formulation

Selecting the appropriate Povidone grade depends on the target formulation, processing method, desired viscosity, binding requirement and compatibility with active ingredients.

Povidone Grade	K Value Range	Viscous Average Molecular Weight	Typical Selection Direction
PVP K15	12.75–17.25	8,000–12,000	Lower-molecular-weight PVP for formulations requiring lower solution viscosity and efficient dissolution
PVP K17	15.3–18.36	10,000–16,000	Suitable for low-viscosity systems where solubility and formulation compatibility are important
PVP K25	22.5–27.0	30,000–40,000	A mid-range grade for granulation, binding and formulation stabilization evaluation
PVP K30	27.0–32.4	45,000–58,000	Commonly considered for tablet binding, granulation, liquid formulations and film-forming applications
PVP K90	81.0–97.2	1,000,000–1,500,000	High-molecular-weight PVP for higher-viscosity, stronger binding, thickening and stabilization requirements

The final grade should be selected through formulation trials, especially when the product is used with sensitive APIs, high drug loads, unusual solvent systems or specialized manufacturing processes.

Povidone Grades Available from Yuking

Povidone K15

Povidone K15 is a lower-molecular-weight PVP grade suitable for formulations where lower solution viscosity and good solubility are required. It can be evaluated for liquid preparations, dispersion systems, solubilization support and other pharmaceutical applications requiring a water-soluble functional polymer.

View Povidone K15 / K17 / K25 / K30 Specifications

Povidone K17

Povidone K17 offers a low molecular weight profile and may be selected when formulators require a balance between solubility, manageable viscosity and polymer functionality. It can be assessed for oral liquid systems, stabilizing applications and pharmaceutical processing support.

View Povidone K15 / K17 / K25 / K30 Specifications

Povidone K25

Povidone K25 is a mid-range molecular-weight grade that can be evaluated for wet granulation, tablet binding and formulation stabilization. Its viscosity profile makes it a practical option for pharmaceutical manufacturers comparing different PVP grades during development and scale-up.

View Povidone K15 / K17 / K25 / K30 Specifications

Povidone K30

Povidone K30 is widely used as a pharmaceutical PVP grade for tablet and granule formulations. It can support wet granulation, binding, liquid preparation stabilization, dispersion and film-forming applications. It may also be considered during the development of formulations containing poorly soluble active ingredients.

View Povidone K15 / K17 / K25 / K30 Specifications

Povidone K90

Povidone K90 is a high-molecular-weight PVP grade for applications requiring higher viscosity, enhanced binding, thickening or stabilization performance. In pharmaceutical formulations, it can be evaluated as a tablet binder, stabilizer for enzyme or heat-sensitive drugs, and co-precipitation aid for poorly soluble drugs.

View Povidone K90 Specifications

Pharmaceutical Functions of Povidone

Povidone can serve different functions depending on the grade, dosage form and formulation design.

Tablet and Granule Binder

PVP can be used as a binder in tablet and granule manufacturing. It helps create cohesive granules and supports tablet integrity during production. K25, K30 and K90 may be evaluated when higher binding performance is required.

Stabilizer for Sensitive Ingredients

Povidone can be used in formulations containing enzymes, heat-sensitive ingredients or other components that require stabilization support. Grade selection should consider the solvent system, process temperature and final dosage form.

Solubilization and Co-Precipitation Support

For poorly soluble active ingredients, Povidone may be evaluated as a solubilization aid or co-precipitation polymer. Compatibility and performance should be confirmed through formulation testing.

Film-Forming Polymer

PVP provides film-forming properties and may be used in pharmaceutical coating or other formulation systems where a water-soluble polymer film is needed.

Dispersing and Suspension Support

In liquid preparations, Povidone may help support dispersion and formulation stability. The appropriate grade depends on target viscosity, particle characteristics and storage requirements.

Typical Pharmaceutical Applications

Povidone K Series can be evaluated for:

• Tablet wet granulation

• Tablet binding

• Granule production

• Oral liquid preparations

• Suspension and dispersion systems

• Film coating systems

• Stabilization of enzymes and heat-sensitive drugs

• Co-precipitation systems for poorly soluble drugs

• Pharmaceutical formulation development and scale-up studies

Key Quality Parameters

Yuking Povidone K Series is supplied with key quality parameters relevant to pharmaceutical formulation evaluation. Typical published control items include:

• K value

• Viscous average molecular weight

• pH value of 5% aqueous solution

• Aldehydes

• Peroxides

• Hydrazine

• N-Vinyl-2-pyrrolidone

• 2-pyrrolidone / α-pyrrolidone

• Moisture

• Sulfated ash

• Nitrogen content

• Heavy metals

For the latest grade-specific specification, please request the relevant TDS and Certificate of Analysis before qualification.

Quality and Regulatory Documentation Support

For pharmaceutical projects, documentation can be as important as product performance. Yuking can discuss the availability of relevant product information and supporting documents for your target market and qualification process.

Available support may include:

• Technical Data Sheet

• Safety Data Sheet

• Certificate of Analysis

• Product specification sheet

• Kosher documentation

• Halal documentation

• DMF-related support

• CEP-related support

• EXCiPACT GMP-related information

• ISO-related information

• Supplier qualification support

Please specify your destination country, dosage form and required documentation when submitting an inquiry. Document availability should be confirmed for the exact Povidone grade and intended market.

Povidone, Crospovidone or Copovidone: Which One Do You Need?

Povidone is a water-soluble functional polymer typically selected for binding, film-forming, stabilization and solubilization-related formulation needs.

When your primary requirement is rapid tablet disintegration, consider Crospovidone. Crospovidone is a cross-linked PVP material designed to absorb water and swell without forming a high-viscosity gel, making it suitable for tablet disintegration applications.

When you are developing a direct-compression formulation and need a dry binder, consider Copovidone VP/VA 64. This VP/VA copolymer can be evaluated for direct tablet compression where tablet hardness and processing performance are important.

Why Choose Yuking for Povidone Supply?

Yuking Technologies focuses on PVP polymers and functional additives, with research, production, application and sales support. The company reports more than 100 patents, 9 production lines and an annual production capacity of 20,000 tons across its product range.

For pharmaceutical PVP projects, Yuking can support customers who need to compare grades, evaluate formulation suitability, request technical documentation or establish long-term supply cooperation.

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Supply Information

Standard Packaging: 25 kg cardboard drum
Storage Conditions: Keep shaded and sealed. Protect the material from moisture.
Sample Request: Available upon project discussion
Commercial Inquiry: Please provide the required grade, intended application, annual demand, destination country and document requirements.

To help us recommend the most suitable Povidone grade, please include:

• Required PVP grade or target K value

• Dosage form or intended application

• Existing formulation challenge

• Required regulatory documentation

• Estimated annual usage

• Target country or market

• Sample, pilot-scale or commercial requirement

Request TDS, Sample or Quotation

Frequently Asked Questions

What is the difference between Povidone K30 and Povidone K90?

The main difference is molecular weight and viscosity. Povidone K90 has a substantially higher molecular weight and is generally considered when higher viscosity, stronger binding or thickening performance is needed. Povidone K30 is often evaluated for tablet binding, granulation, liquid formulations and film-forming applications.

How do I choose between PVP K15, K17, K25, K30 and K90?

Start with your target application, desired solution viscosity, binding requirement and process route. Lower K values are generally selected for lower-viscosity systems, while K30 and K90 are more often evaluated where stronger binding or higher viscosity is required. Formulation testing is recommended before final approval.

Is Povidone the same as Crospovidone?

No. Povidone is water-soluble and can be used for binding, film-forming, stabilization and solubilization support. Crospovidone is a cross-linked, insoluble PVP material mainly used as a tablet disintegrant.

Can Povidone be used for direct compression?

Povidone may be used in formulation development depending on the process and formulation design. For direct-compression systems requiring a dry binder, Copovidone VP/VA 64 may be a more relevant option to evaluate.

What documents can I request before placing an order?

You may request product specifications, TDS, SDS, recent COA and relevant quality or regulatory documents. Please confirm required documents for the specific grade and destination market before qualification.

How is Povidone packed and stored?

Yuking Povidone K Series is supplied in 25 kg cardboard drums. The product should be stored in a shaded, sealed environment and protected from moisture.

Start Your Povidone Project with Yuking

Whether you are qualifying an alternative PVP supplier, developing a new tablet formulation, evaluating K30 versus K90, or sourcing pharmaceutical Povidone for long-term production, Yuking can help you identify the suitable grade and provide the relevant product information.

Contact Yuking for Povidone PVP K Series